Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

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Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 0.0000
uM
 72
hr
 2 726 337 0.3680 0.3617 0.4642 0.4540
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 0.0000
uM
 72
hr
 3 715 303 0.3898 0.3617 0.4238 0.4540
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 0.3160
uM
 72
hr
 1 699 305 0.3728 0.4027 0.4363 0.4226
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 0.3160
uM
 72
hr
 2 726 290 0.4125 0.4027 0.3994 0.4226
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 0.3160
uM
 72
hr
 3 787 340 0.4229 0.4027 0.4320 0.4226
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 1.0000
uM
 72
hr
 1 692 267 0.4021 0.3491 0.3858 0.3549
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 1.0000
uM
 72
hr
 2 623 194 0.4059 0.3491 0.3114 0.3549
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 1.0000
uM
 72
hr
 3 400 147 0.2394 0.3491 0.3675 0.3549
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 3.1600
uM
 72
hr
 1 713 211 0.4749 0.3709 0.2959 0.3022
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 3.1600
uM
 72
hr
 2 602 214 0.3671 0.3709 0.3555 0.3022
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 3.1600
uM
 72
hr
 3 384 98 0.2706 0.3709 0.2552 0.3022
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 0.0000
uM
 72
hr
 1 613 280 0.3150 0.3557 0.4568 0.4268
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 0.0000
uM
 72
hr
 2 600 239 0.3415 0.3557 0.3983 0.4268
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 0.0000
uM
 72
hr
 3 755 321 0.4106 0.3557 0.4252 0.4268
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 0.3160
uM
 72
hr
 1 565 215 0.3311 0.3649 0.3805 0.3754
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 0.3160
uM
 72
hr
 2 670 245 0.4021 0.3649 0.3657 0.3754
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 0.3160
uM
 72
hr
 3 616 234 0.3614 0.3649 0.3799 0.3754
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 1.0000
uM
 72
hr
 1 819 300 0.4910 0.3683 0.3663 0.3603
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 1.0000
uM
 72
hr
 2 584 219 0.3453 0.3683 0.3750 0.3603
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 1.0000
uM
 72
hr
 3 430 146 0.2687 0.3683 0.3395 0.3603
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 3.1600
uM
 72
hr
 1 585 174 0.3888 0.3299 0.2974 0.2945
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 3.1600
uM
 72
hr
 2 495 160 0.3169 0.3299 0.3232 0.2945
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 3.1600
uM
 72
hr
 3 407 107 0.2838 0.3299 0.2629 0.2945
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 1 523 240 0.2677 0.2718 0.4589 0.4581
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 2 524 251 0.2583 0.2718 0.4790 0.4581