Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

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Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
WM-115 Vemurafenib Trametinib JNK-IN-8 0.0000 0.0000 0.3160
uM
 72
hr
 3 4110 265 0.9575 0.9709 0.0645 0.0651
WM-115 Vemurafenib Trametinib JNK-IN-8 0.0000 0.0000 1.0000
uM
 72
hr
 1 3989 257 0.9294 0.9135 0.0644 0.0688
WM-115 Vemurafenib Trametinib JNK-IN-8 0.0000 0.0000 1.0000
uM
 72
hr
 2 3983 303 0.9164 0.9135 0.0761 0.0688
WM-115 Vemurafenib Trametinib JNK-IN-8 0.0000 0.0000 1.0000
uM
 72
hr
 3 3847 254 0.8947 0.9135 0.0660 0.0688
WM-115 Vemurafenib Trametinib JNK-IN-8 0.0000 0.0000 3.1600
uM
 72
hr
 1 3633 355 0.8163 0.7484 0.0977 0.0918
WM-115 Vemurafenib Trametinib JNK-IN-8 0.0000 0.0000 3.1600
uM
 72
hr
 2 3280 283 0.7463 0.7484 0.0863 0.0918
WM-115 Vemurafenib Trametinib JNK-IN-8 0.0000 0.0000 3.1600
uM
 72
hr
 3 3017 276 0.6826 0.7484 0.0915 0.0918
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 0.0000
uM
 72
hr
 1 2084 606 0.3681 0.3785 0.2908 0.2913
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 0.0000
uM
 72
hr
 2 2130 598 0.3815 0.3785 0.2808 0.2913
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 0.0000
uM
 72
hr
 3 2222 672 0.3860 0.3785 0.3024 0.2913
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 0.3160
uM
 72
hr
 1 2038 708 0.3312 0.3306 0.3474 0.3500
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 0.3160
uM
 72
hr
 2 2124 785 0.3334 0.3306 0.3696 0.3500
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 0.3160
uM
 72
hr
 3 1970 656 0.3272 0.3306 0.3330 0.3500
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 1.0000
uM
 72
hr
 1 1960 722 0.3083 0.3088 0.3684 0.3580
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 1.0000
uM
 72
hr
 2 1974 708 0.3153 0.3088 0.3587 0.3580
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 1.0000
uM
 72
hr
 3 1862 646 0.3028 0.3088 0.3469 0.3580
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 3.1600
uM
 72
hr
 1 1756 1052 0.1753 0.1729 0.5991 0.5842
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 3.1600
uM
 72
hr
 2 1693 975 0.1788 0.1729 0.5759 0.5842
WM-115 Vemurafenib Trametinib JNK-IN-8 0.1000 0.0100 3.1600
uM
 72
hr
 3 1565 904 0.1646 0.1729 0.5776 0.5842
WM-115 Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.0000
uM
 72
hr
 1 1948 617 0.3315 0.3286 0.3167 0.3294
WM-115 Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.0000
uM
 72
hr
 2 1926 645 0.3190 0.3286 0.3349 0.3294
WM-115 Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.0000
uM
 72
hr
 3 2030 683 0.3354 0.3286 0.3365 0.3294
WM-115 Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.3160
uM
 72
hr
 1 1876 768 0.2759 0.2823 0.4094 0.4075
WM-115 Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.3160
uM
 72
hr
 2 1967 781 0.2953 0.2823 0.3971 0.4075
WM-115 Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.3160
uM
 72
hr
 3 1896 789 0.2757 0.2823 0.4161 0.4075