Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule 1 | Small Molecule 2 | Small Molecule 3 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol 3 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 0.0000 | uM | 72 | hr | 1 | 15785 | 755 | 0.9659 | 1.0000 | 0.0478 | 0.0508 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 0.0000 | uM | 72 | hr | 2 | 15978 | 849 | 0.9722 | 1.0000 | 0.0531 | 0.0508 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 0.0000 | uM | 72 | hr | 3 | 17422 | 897 | 1.0619 | 1.0000 | 0.0515 | 0.0508 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 0.3160 | uM | 72 | hr | 1 | 3999 | 254 | 0.2407 | 0.2809 | 0.0635 | 0.0601 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 0.3160 | uM | 72 | hr | 2 | 4717 | 279 | 0.2852 | 0.2809 | 0.0591 | 0.0601 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 0.3160 | uM | 72 | hr | 3 | 5232 | 302 | 0.3168 | 0.2809 | 0.0577 | 0.0601 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 1.0000 | uM | 72 | hr | 1 | 2100 | 97 | 0.1287 | 0.1268 | 0.0462 | 0.0491 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 1.0000 | uM | 72 | hr | 2 | 2015 | 111 | 0.1224 | 0.1268 | 0.0551 | 0.0491 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 1.0000 | uM | 72 | hr | 3 | 2110 | 97 | 0.1294 | 0.1268 | 0.0460 | 0.0491 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 3.1600 | uM | 72 | hr | 1 | 3039 | 126 | 0.1872 | 0.1595 | 0.0415 | 0.0410 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 3.1600 | uM | 72 | hr | 2 | 2717 | 113 | 0.1673 | 0.1595 | 0.0416 | 0.0410 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.0000 | 0.0000 | 3.1600 | uM | 72 | hr | 3 | 2009 | 80 | 0.1240 | 0.1595 | 0.0398 | 0.0410 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 0.0000 | uM | 72 | hr | 1 | 2248 | 244 | 0.1288 | 0.1325 | 0.1085 | 0.1040 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 0.0000 | uM | 72 | hr | 2 | 2377 | 236 | 0.1376 | 0.1325 | 0.0993 | 0.1040 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 0.0000 | uM | 72 | hr | 3 | 2277 | 237 | 0.1311 | 0.1325 | 0.1041 | 0.1040 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 0.3160 | uM | 72 | hr | 1 | 766 | 180 | 0.0377 | 0.0429 | 0.2350 | 0.2266 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 0.3160 | uM | 72 | hr | 2 | 890 | 196 | 0.0446 | 0.0429 | 0.2202 | 0.2266 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 0.3160 | uM | 72 | hr | 3 | 931 | 209 | 0.0464 | 0.0429 | 0.2245 | 0.2266 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 1.0000 | uM | 72 | hr | 1 | 772 | 164 | 0.0391 | 0.0336 | 0.2124 | 0.2228 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 1.0000 | uM | 72 | hr | 2 | 639 | 159 | 0.0308 | 0.0336 | 0.2488 | 0.2228 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 1.0000 | uM | 72 | hr | 3 | 608 | 126 | 0.0310 | 0.0336 | 0.2072 | 0.2228 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 3.1600 | uM | 72 | hr | 1 | 997 | 194 | 0.0516 | 0.0393 | 0.1946 | 0.1867 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 3.1600 | uM | 72 | hr | 2 | 742 | 124 | 0.0397 | 0.0393 | 0.1671 | 0.1867 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.1000 | 0.0100 | 3.1600 | uM | 72 | hr | 3 | 519 | 103 | 0.0267 | 0.0393 | 0.1985 | 0.1867 |
A-375 | Vemurafenib | Trametinib | Dasatinib | 0.3160 | 0.0316 | 0.0000 | uM | 72 | hr | 1 | 1997 | 255 | 0.1119 | 0.1296 | 0.1277 | 0.1185 |