Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Trametinib Defactinib 3.1600 0.3160 1.0000
uM
 72
hr
 2 356 158 0.1912 0.1986 0.4438 0.4158
MMAC-SF Vemurafenib Trametinib PF562271 3.1600 0.3160 1.0000
uM
 72
hr
 2 356 167 0.1634 0.1628 0.4691 0.4419
MMAC-SF Vemurafenib Trametinib PF562271 0.3160 0.0316 1.0000
uM
 72
hr
 2 359 152 0.1790 0.1951 0.4234 0.4396
MZ7-mel Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 2 360 69 0.0873 0.0797 0.1917 0.2019
MMAC-SF Vemurafenib Trametinib PF562271 1.0000 0.1000 1.0000
uM
 72
hr
 2 361 159 0.1746 0.1784 0.4404 0.4506
MZ7-mel Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 1 364 75 0.0867 0.0797 0.2060 0.2019
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 3.1600
uM
 72
hr
 2 365 92 0.2703 0.2729 0.2521 0.2392
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.3160
uM
 72
hr
 2 366 118 0.2455 0.2574 0.3224 0.3200
MMAC-SF Vemurafenib Trametinib Saracatinib 0.1000 0.0100 1.0000
uM
 72
hr
 3 367 103 0.2614 0.3693 0.2807 0.2801
MMAC-SF Vemurafenib Trametinib Saracatinib 0.1000 0.0100 3.1600
uM
 72
hr
 3 367 84 0.2802 0.4168 0.2289 0.2703
MMAC-SF Vemurafenib Trametinib JNK-IN-8 1.0000 0.1000 1.0000
uM
 72
hr
 3 373 99 0.2713 0.3937 0.2654 0.2879
MMAC-SF Vemurafenib Trametinib Defactinib 0.1000 0.0100 3.1600
uM
 72
hr
 2 374 238 0.1313 0.1329 0.6364 0.6191
MMAC-SF Vemurafenib Trametinib PF562271 0.3160 0.0316 3.1600
uM
 72
hr
 1 374 194 0.1556 0.1329 0.5187 0.4906
MMAC-SF Vemurafenib Trametinib Defactinib 1.0000 0.1000 1.0000
uM
 72
hr
 2 376 167 0.2018 0.2053 0.4441 0.4547
MMAC-SF Vemurafenib Trametinib Defactinib 1.0000 0.1000 3.1600
uM
 72
hr
 1 376 183 0.1864 0.1361 0.4867 0.5198
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 3 379 152 0.2148 0.2397 0.4011 0.3798
MMAC-SF Vemurafenib Trametinib Saracatinib 0.3160 0.0316 3.1600
uM
 72
hr
 3 379 111 0.2653 0.3977 0.2929 0.3010
MMAC-SF Vemurafenib Trametinib JNK-IN-8 1.0000 0.1000 3.1600
uM
 72
hr
 3 381 88 0.2901 0.3373 0.2310 0.2733
MMAC-SF Vemurafenib Trametinib Saracatinib 3.1600 0.3160 1.0000
uM
 72
hr
 2 381 151 0.2277 0.2512 0.3963 0.3722
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 3 382 87 0.2791 0.2904 0.2277 0.2383
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 2 383 70 0.2961 0.2904 0.1828 0.2383
MMAC-SF Vemurafenib Trametinib Dasatinib 0.3160 0.0316 3.1600
uM
 72
hr
 3 384 98 0.2706 0.3709 0.2552 0.3022
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 2 386 136 0.2365 0.2397 0.3523 0.3798
MMAC-SF Vemurafenib Trametinib Defactinib 0.3160 0.0316 1.0000
uM
 72
hr
 2 387 186 0.1941 0.1699 0.4806 0.5080
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.3160
uM
 72
hr
 1 389 120 0.2663 0.2574 0.3085 0.3200