Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset - HMS LINCS Database

Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

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Cell	Small Molecule 1	Small Molecule 2	Small Molecule 3	Small Mol 1 Concentration	Small Mol 2 Concentration	Small Mol 3 Concentration	Small Mol Conc Unit	Time Point	Time Point Unit	Replicate	Total Number of Cells (Nuclei)	Number of Apoptotic Cells	Relative Viability	Mean Relative Viability	Apoptosis Fraction	Mean Apoptosis Fraction
A-375	Vemurafenib	Trametinib	Belinostat	0.0000	0.0000	0.0000	uM	72	hr	2	15480	1512	1.0561	1.0000	0.0977	0.1003
A-375	Vemurafenib	Trametinib	I-BET	0.0000	0.0000	0.0000	uM	72	hr	3	14201	1526	0.9096	1.0000	0.1075	0.0842
A-375	Vemurafenib	Trametinib	I-BET	0.0000	0.0000	0.0000	uM	72	hr	1	15279	1529	0.9867	1.0000	0.1001	0.0842
COLO 858	Vemurafenib	Trametinib	Dasatinib	3.1600	0.3160	0.0000	uM	72	hr	3	1665	1566	0.0164	0.0156	0.9405	0.9275
COLO 858	Vemurafenib	Trametinib	Defactinib	3.1600	0.3160	0.0000	uM	72	hr	2	1636	1567	0.0097	0.0136	0.9578	0.9358
A-375	Vemurafenib	Trametinib	Belinostat	0.0000	0.0000	0.0000	uM	72	hr	3	15897	1615	1.0798	1.0000	0.1016	0.1003
A-375	Vemurafenib	Trametinib	I-BET151	0.0000	0.0000	0.0000	uM	72	hr	3	16303	1628	1.0189	1.0000	0.0999	0.1003
COLO 858	Vemurafenib	Trametinib	Defactinib	3.1600	0.3160	0.0000	uM	72	hr	3	1724	1632	0.0129	0.0136	0.9466	0.9358
COLO 858	Vemurafenib	Trametinib	Defactinib	3.1600	0.3160	1.0000	uM	72	hr	1	1719	1644	0.0106	0.0087	0.9564	0.9527
A-375	Vemurafenib	Trametinib	I-BET151	0.0000	0.0000	0.0000	uM	72	hr	2	16450	1693	1.0246	1.0000	0.1029	0.1003