Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib Trametinib Defactinib 3.1600 0.3160 3.1600
uM
 72
hr
 2 737 194 0.1611 0.1687 0.2632 0.2871
MZ7-mel Vemurafenib Trametinib Defactinib 3.1600 0.3160 3.1600
uM
 72
hr
 3 843 257 0.1739 0.1687 0.3049 0.2871
MZ7-mel Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.0000
uM
 72
hr
 2 1725 939 0.2072 0.1960 0.5443 0.5353
MZ7-mel Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.0000
uM
 72
hr
 3 1688 868 0.2161 0.1960 0.5142 0.5353
A-375 Vemurafenib Trametinib Saracatinib 3.1600 0.3160 0.3160
uM
 72
hr
 1 1779 195 0.0941 0.0889 0.1096 0.1191
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 1.0000
uM
 72
hr
 3 923 892 0.0051 0.0049 0.9664 0.9743
A-375 Vemurafenib Trametinib Saracatinib 3.1600 0.3160 0.0000
uM
 72
hr
 1 2462 353 0.1253 0.1328 0.1434 0.1351
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 1 711 706 0.0008 0.0020 0.9930 0.9824
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 3 1665 1566 0.0164 0.0156 0.9405 0.9275
WM-115 Vemurafenib Trametinib Defactinib 3.1600 0.3160 0.0000
uM
 72
hr
 1 1466 845 0.1610 0.1825 0.5764 0.5506
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 2 1118 1048 0.0116 0.0156 0.9374 0.9275
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 1 1185 1072 0.0187 0.0156 0.9046 0.9275
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 1.0000
uM
 72
hr
 2 1237 1209 0.0046 0.0049 0.9774 0.9743
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 2 755 735 0.0033 0.0020 0.9735 0.9824
WM-115 Vemurafenib Trametinib Defactinib 3.1600 0.3160 0.3160
uM
 72
hr
 3 1254 822 0.1120 0.1129 0.6555 0.6197
COLO 858 Vemurafenib Trametinib Defactinib 3.1600 0.3160 3.1600
uM
 72
hr
 1 958 901 0.0080 0.0069 0.9405 0.9329
COLO 858 Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.0000
uM
 72
hr
 1 1254 1139 0.0174 0.0186 0.9083 0.9092
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 1.0000
uM
 72
hr
 1 1387 1358 0.0048 0.0049 0.9791 0.9743
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 3 626 614 0.0020 0.0020 0.9808 0.9824
COLO 858 Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.0000
uM
 72
hr
 2 1412 1324 0.0133 0.0186 0.9377 0.9092
COLO 858 Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 1.0000
uM
 72
hr
 1 1491 1204 0.0433 0.0226 0.8075 0.8932
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 1 707 693 0.0023 0.0030 0.9802 0.9776
COLO 858 Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 1.0000
uM
 72
hr
 3 1175 1082 0.0140 0.0226 0.9209 0.8932
MZ7-mel Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 3.1600
uM
 72
hr
 2 608 291 0.0835 0.0835 0.4786 0.4574
MZ7-mel Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 3.1600
uM
 72
hr
 1 729 332 0.1046 0.0835 0.4554 0.4574