Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 3 1665 1566 0.0164 0.0156 0.9405 0.9275
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 1 711 706 0.0008 0.0020 0.9930 0.9824
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 2 755 735 0.0033 0.0020 0.9735 0.9824
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.3160
uM
 72
hr
 3 626 614 0.0020 0.0020 0.9808 0.9824
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 1.0000
uM
 72
hr
 1 1387 1358 0.0048 0.0049 0.9791 0.9743
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 1.0000
uM
 72
hr
 2 1237 1209 0.0046 0.0049 0.9774 0.9743
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 1.0000
uM
 72
hr
 3 923 892 0.0051 0.0049 0.9664 0.9743
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 1 707 693 0.0023 0.0030 0.9802 0.9776
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 2 717 700 0.0028 0.0030 0.9763 0.9776
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 3.1600
uM
 72
hr
 3 975 952 0.0038 0.0030 0.9764 0.9776
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 0.0000
uM
 72
hr
 1 8737 1282 1.0493 1.0000 0.1467 0.1477
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 0.0000
uM
 72
hr
 2 9127 1356 1.0938 1.0000 0.1486 0.1477
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 0.0000
uM
 72
hr
 3 7143 1055 0.8569 1.0000 0.1477 0.1477
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 0.3160
uM
 72
hr
 1 7512 1166 0.8932 0.9286 0.1552 0.1630
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 0.3160
uM
 72
hr
 2 7902 1360 0.9208 0.9286 0.1721 0.1630
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 0.3160
uM
 72
hr
 3 8236 1331 0.9719 0.9286 0.1616 0.1630
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 1.0000
uM
 72
hr
 1 5372 829 0.6394 0.5738 0.1543 0.1547
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 1.0000
uM
 72
hr
 2 4692 764 0.5529 0.5738 0.1628 0.1547
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 1.0000
uM
 72
hr
 3 4407 647 0.5292 0.5738 0.1468 0.1547
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 3.1600
uM
 72
hr
 1 1908 750 0.1630 0.1328 0.3931 0.4089
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 3.1600
uM
 72
hr
 2 1595 664 0.1310 0.1328 0.4163 0.4089
COLO 858 Vemurafenib Trametinib Defactinib 0.0000 0.0000 3.1600
uM
 72
hr
 3 1272 531 0.1043 0.1328 0.4175 0.4089
COLO 858 Vemurafenib Trametinib Defactinib 0.1000 0.0100 0.0000
uM
 72
hr
 1 1452 751 0.0987 0.0901 0.5172 0.5765
COLO 858 Vemurafenib Trametinib Defactinib 0.1000 0.0100 0.0000
uM
 72
hr
 2 1533 890 0.0905 0.0901 0.5806 0.5765
COLO 858 Vemurafenib Trametinib Defactinib 0.1000 0.0100 0.0000
uM
 72
hr
 3 1564 988 0.0811 0.0901 0.6317 0.5765