Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10008-3 | Sorafenib | BAY-439006 | LSM-1008 |  | 216239 |
| 10175-3 | Sunitinib | Sutent; SU11248 | LSM-42800 |  | 3086686 |
| 10102-3 | Taxol | Paclitaxel | LSM-1102 |  | 441276 |
| 10276-1 | TCS 2312 | LSM-6362 |  | 11258443 | |
| 10520-1 | TCS PIM-1 1 |  | 1235170 | ||
| 10277-1 | Temsirolimus | LSM-4295 |  | 148191 | |
| 10278-1 | Topotecan | Hycamtin | LSM-5662 |  | 60700 |
| 10345-3 | Torkinib | PP242 | LSM-6357 |  | 57347681 |
| 10021-5 | Tozasertib | VX680; MK-0457 | LSM-1021 |  | 5494449 |
| 10136-2 | TPCA-1 | LSM-1136 |  | 9903786 | |
| 10142-2 | Trametinib | GSK-1120212; GSK1120212; GSK1120212B; JTP-74057 | LSM-1143 |  | 11707110 |
| 10279-1 | Trichostatin A | LSM-43005 |  | ||
| 10280-1 | Triciribine | LSM-3810 |  | 65399 | |
| 10346-1 | Valproic acid | Depakine | LSM-4620 |  | 3549980 |
| 10281-1 | Vinorelbine | Navelbine | LSM-6302 |  | 5311497 |
| 10282-1 | Vorinostat | suberoylanilide hydroxamic acid (SAHA); Zolinza | LSM-3828 |  | 5311 |
| 10283-1 | XRP44X | AG-G-87906 | LSM-4298 |  | 10339779 |
| 10275-1 | (Z)-4-Hydroxytamoxifen | LSM-43294 |  | 53770298 | |
| 10348-1 | Z-Leu-Leu-Norvalinal | MG-115 | LSM-6358 |  | 9868928 |
| 10096-2 | ZM-447439 | LSM-1096 |  | 9914412 |