Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7870.007 | 0.9449 | 0.9460 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7870.007 | 0.9348 | 0.9359 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7870.007 | 0.8369 | 0.8353 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7870.007 | 0.7459 | 0.7360 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7870.007 | 0.0555 | -0.5051 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7870.007 | 0.0089 | -0.7954 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7870.007 | 0.0043 | -0.8553 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7870.007 | 0.0041 | -0.8598 | 2.0710 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9551.121 | 1.1008 | 1.0713 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9551.121 | 0.9722 | 0.9795 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9551.121 | 1.0415 | 1.0299 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9551.121 | 0.8426 | 0.8789 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9551.121 | 0.5198 | 0.5754 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9551.121 | 0.2400 | 0.1885 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9551.121 | 0.0077 | -0.6616 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9551.121 | 0.0063 | -0.6851 | 2.7416 | |
| MCF 10A | NM | Basal B | Doxorubicin | TOP2 | TOP | 92 | uM | 9551.121 | 0.0055 | -0.6995 | 2.7416 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 7488.078 | 0.9258 | 0.9007 | 1.5130 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 7488.078 | 1.0010 | 1.0013 | 1.5130 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 7488.078 | 0.9331 | 0.9106 | 1.5130 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 7488.078 | 0.8212 | 0.7559 | 1.5130 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 0.147 | uM | 7488.078 | 0.6441 | 0.4954 | 1.5130 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 0.736 | uM | 7488.078 | 0.4075 | 0.1049 | 1.5130 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 3.68 | uM | 7488.078 | 0.0345 | -0.7840 | 1.5130 | |
| MCF 10F | NM | - | Doxorubicin | TOP2 | TOP | 18.4 | uM | 7488.078 | 0.0438 | -0.7471 | 1.5130 |