Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9759.037 | 1.0408 | 1.0628 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9759.037 | 0.9541 | 0.9288 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9759.037 | 0.6515 | 0.4364 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9759.037 | 0.4410 | 0.0625 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9759.037 | 0.4289 | 0.0400 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9759.037 | 0.4112 | 0.0065 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9759.037 | 0.2969 | -0.2172 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9759.037 | 0.1203 | -0.6105 | 1.2944 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9760.037 | 0.9956 | 0.9907 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9760.037 | 1.1131 | 1.2415 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9760.037 | 0.9073 | 0.8033 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9760.037 | 0.8070 | 0.5920 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9760.037 | 0.5555 | 0.0699 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9760.037 | 0.5036 | -0.0360 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9760.037 | 0.4757 | -0.0929 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9760.037 | 0.3219 | -0.4014 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9760.037 | 0.1247 | -0.7818 | 0.9398 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 10127.037 | 1.1021 | 1.2866 | 0.7262 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 10127.037 | 0.7476 | 0.3398 | 0.7262 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 10127.037 | 0.9970 | 0.9917 | 0.7262 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 10127.037 | 0.7824 | 0.4264 | 0.7262 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 10127.037 | 0.6554 | 0.1178 | 0.7262 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 10127.037 | 0.6204 | 0.0365 | 0.7262 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 10127.037 | 0.5134 | -0.2014 | 0.7262 | |
| SK-BR-3 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 10127.037 | 0.3782 | -0.4757 | 0.7262 |