Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7871.05 | 0.9537 | 0.9278 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7871.05 | 0.7085 | 0.5309 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7871.05 | 0.1516 | -0.5371 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7871.05 | 0.1263 | -0.5983 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 4 | uM | 7871.05 | 0.1223 | -0.6082 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 20 | uM | 7871.05 | 0.1179 | -0.6190 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 100 | uM | 7871.05 | 0.0974 | -0.6716 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7872.05 | 1.0379 | 1.0506 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7872.05 | 1.0223 | 1.0298 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7872.05 | 1.0058 | 1.0077 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7872.05 | 0.8488 | 0.7916 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7872.05 | 0.2397 | -0.2332 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7872.05 | 0.2240 | -0.2672 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 4 | uM | 7872.05 | 0.1942 | -0.3341 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 20 | uM | 7872.05 | 0.1350 | -0.4784 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 100 | uM | 7872.05 | 0.0669 | -0.6743 | 1.4902 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9566.037 | 1.1043 | 1.0845 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9566.037 | 1.0726 | 1.0593 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9566.037 | 0.9940 | 0.9950 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9566.037 | 0.3057 | 0.2202 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9566.037 | 0.0820 | -0.2950 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9566.037 | 0.0796 | -0.3037 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 4 | uM | 9566.037 | 0.0730 | -0.3284 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 20 | uM | 9566.037 | 0.0585 | -0.3876 | 2.3981 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 100 | uM | 9566.037 | 0.0122 | -0.6811 | 2.3981 |