Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 2.67 | uM | 10520.136 | 1.0020 | 1.0010 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 13.3 | uM | 10520.136 | 0.8893 | 0.9427 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 66.7 | uM | 10520.136 | 1.0699 | 1.0338 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 333 | uM | 10520.136 | 0.8789 | 0.9370 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 1670 | uM | 10520.136 | 0.9245 | 0.9615 | 4.0331 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 0.00427 | uM | 10579.136 | 1.0487 | 1.1433 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 0.0213 | uM | 10579.136 | 1.1359 | 1.4073 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 0.107 | uM | 10579.136 | 1.0260 | 1.0760 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 0.533 | uM | 10579.136 | 1.0306 | 1.0897 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 2.67 | uM | 10579.136 | 1.0926 | 1.2749 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 13.3 | uM | 10579.136 | 1.0631 | 1.1861 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 66.7 | uM | 10579.136 | 1.0733 | 1.2167 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 333 | uM | 10579.136 | 1.0468 | 1.1375 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Celecoxib | COX2 | COX | 1670 | uM | 10579.136 | 1.1207 | 1.3605 | 0.6876 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.00427 | uM | 10580.136 | 0.9056 | 0.7428 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.0213 | uM | 10580.136 | 0.8840 | 0.6855 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.107 | uM | 10580.136 | 0.9421 | 0.8411 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.533 | uM | 10580.136 | 0.9018 | 0.7327 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 2.67 | uM | 10580.136 | 0.9448 | 0.8484 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 13.3 | uM | 10580.136 | 0.9588 | 0.8866 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 66.7 | uM | 10580.136 | 0.9655 | 0.9048 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 333 | uM | 10580.136 | 0.9834 | 0.9541 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Celecoxib | COX2 | COX | 1670 | uM | 10580.136 | 0.9716 | 0.9217 | 0.7205 | |
| 184A1 | NM | Basal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7787.018 | 1.1731 | 2.0469 | 0.3791 | |
| 184A1 | NM | Basal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7787.018 | 0.7954 | 0.0935 | 0.3791 |