Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9158.037 | 1.0566 | 1.2484 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9158.037 | 1.0177 | 1.0761 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9158.037 | 1.0599 | 1.2632 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9158.037 | 0.5383 | -0.4642 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9158.037 | 0.3600 | -0.7723 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9158.037 | 0.4017 | -0.7126 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9158.037 | 0.3865 | -0.7351 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9158.037 | 0.6593 | -0.1754 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9158.037 | 0.9747 | 0.8937 | 0.4702 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9163.037 | 1.0245 | 1.0943 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9163.037 | 1.0374 | 1.1445 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9163.037 | 1.0122 | 1.0466 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9163.037 | 0.6095 | -0.2199 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9163.037 | 0.3206 | -0.7702 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9163.037 | 0.3177 | -0.7741 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9163.037 | 0.2851 | -0.8161 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9163.037 | 0.2243 | -0.8835 | 0.5258 | |
| BT-474 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9163.037 | 0.1189 | -0.9651 | 0.5258 | |
| BT-483 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7801.037 | 1.0020 | 1.0116 | 0.3490 | |
| BT-483 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7801.037 | 0.9847 | 0.9137 | 0.3490 | |
| BT-483 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7801.037 | 1.0660 | 1.4021 | 0.3490 | |
| BT-483 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7801.037 | 1.1062 | 1.6706 | 0.3490 | |
| BT-483 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7801.037 | 0.8140 | 0.1089 | 0.3490 | |
| BT-483 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7801.037 | 0.7300 | -0.1884 | 0.3490 | |
| BT-483 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7801.037 | 0.7087 | -0.2542 | 0.3490 |