Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15319.203 | 0.9123 | 0.9199 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15319.203 | 1.0708 | 1.0619 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15319.203 | 1.0708 | 1.0619 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15319.203 | 0.9040 | 0.9120 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15319.203 | 0.9040 | 0.9120 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15319.203 | 0.6020 | 0.5951 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15319.203 | 0.6020 | 0.5951 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15319.203 | 0.3995 | 0.3285 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15319.203 | 0.3995 | 0.3285 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15319.203 | 0.1586 | -0.1199 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15319.203 | 0.1586 | -0.1199 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15319.203 | 0.0181 | -0.6660 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15319.203 | 0.0181 | -0.6660 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15319.203 | 0.0182 | -0.6648 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15319.203 | 0.0182 | -0.6648 | 2.2432 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7489.074 | 0.9843 | 0.9854 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7489.074 | 0.9843 | 0.9854 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7489.074 | 0.9769 | 0.9785 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7489.074 | 0.9769 | 0.9785 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7489.074 | 0.9313 | 0.9352 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7489.074 | 0.9313 | 0.9352 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7489.074 | 0.6514 | 0.6403 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7489.074 | 0.6514 | 0.6403 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7489.074 | 0.2510 | 0.0551 | 2.1617 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7489.074 | 0.2510 | 0.0551 | 2.1617 |