Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7487.074 | 0.0188 | -0.8784 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7487.074 | 0.0188 | -0.8784 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 167 | uM | 7487.074 | 0.0123 | -0.9095 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 167 | uM | 7487.074 | 0.0123 | -0.9095 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14751.203 | 0.9411 | 0.9350 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14751.203 | 0.9411 | 0.9350 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14751.203 | 0.7193 | 0.6720 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14751.203 | 0.7193 | 0.6720 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14751.203 | 0.8334 | 0.8113 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14751.203 | 0.8334 | 0.8113 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14751.203 | 0.3470 | 0.1248 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14751.203 | 0.3470 | 0.1248 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14751.203 | 0.1410 | -0.3106 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14751.203 | 0.1410 | -0.3106 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14751.203 | 0.0509 | -0.6041 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14751.203 | 0.0509 | -0.6041 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14751.203 | 0.0442 | -0.6329 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14751.203 | 0.0442 | -0.6329 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14751.203 | 0.0486 | -0.6137 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14751.203 | 0.0486 | -0.6137 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14751.203 | 0.0209 | -0.7561 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14751.203 | 0.0209 | -0.7561 | 1.8391 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15319.203 | 0.9938 | 0.9945 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15319.203 | 0.9938 | 0.9945 | 2.2432 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15319.203 | 0.9123 | 0.9199 | 2.2432 |