Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15304.203 | 0.4133 | -0.3892 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15304.203 | 0.3248 | -0.5580 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15304.203 | 0.3248 | -0.5580 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15304.203 | 0.1855 | -0.7916 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15304.203 | 0.1855 | -0.7916 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15304.203 | 0.1357 | -0.8630 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15304.203 | 0.1357 | -0.8630 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15304.203 | 0.1296 | -0.8712 | 0.7449 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15304.203 | 0.1296 | -0.8712 | 0.7449 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7447.074 | 1.0199 | 1.0257 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7447.074 | 1.0199 | 1.0257 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7447.074 | 0.9763 | 0.9692 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7447.074 | 0.9763 | 0.9692 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7447.074 | 0.9274 | 0.9045 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7447.074 | 0.9274 | 0.9045 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7447.074 | 0.3660 | 0.0418 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7447.074 | 0.3660 | 0.0418 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7447.074 | 0.0468 | -0.7256 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7447.074 | 0.0468 | -0.7256 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7447.074 | 0.0384 | -0.7589 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7447.074 | 0.0384 | -0.7589 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7447.074 | 0.0393 | -0.7552 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7447.074 | 0.0393 | -0.7552 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7447.074 | 0.0552 | -0.6946 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7447.074 | 0.0552 | -0.6946 | 1.5411 |