Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14284.189 | 0.0045 | -0.9595 | 1.3873 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14284.189 | 0.0031 | -0.9692 | 1.3873 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14652.189 | 0.9546 | 0.9606 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14652.189 | 0.9529 | 0.9591 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14652.189 | 0.9824 | 0.9848 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14652.189 | 0.9766 | 0.9798 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14652.189 | 0.9934 | 0.9943 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14652.189 | 0.8576 | 0.8725 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14652.189 | 1.0479 | 1.0406 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14652.189 | 0.0106 | -0.7158 | 2.3317 | |
| SUM149PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14652.189 | 0.0096 | -0.7273 | 2.3317 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14176.189 | 1.6080 | 5.0593 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14176.189 | 1.0262 | 1.1246 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14176.189 | 0.9164 | 0.6311 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14176.189 | 1.1203 | 1.6070 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14176.189 | 1.9453 | 8.4502 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14176.189 | 0.1203 | -0.9857 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14176.189 | 0.0016 | -1.0000 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14176.189 | 0.0137 | -0.9999 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14176.189 | 0.0120 | -0.9999 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14287.189 | 1.0010 | 1.0008 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14287.189 | 0.9636 | 0.9693 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14287.189 | 0.9965 | 0.9971 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14287.189 | 0.8646 | 0.8821 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14287.189 | 0.9570 | 0.9637 | 2.3947 |