Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.000853	uM	14161.189	0.9653	0.9368	1.1003
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.00427	uM	14161.189	0.9703	0.9460	1.1003
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.0213	uM	14161.189	0.9679	0.9416	1.1003
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.107	uM	14161.189	0.8725	0.7669	1.1003
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.533	uM	14161.189	0.4537	-0.0249	1.1003
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	2.67	uM	14161.189	0.0390	-0.8953	1.1003
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	13.3	uM	14161.189	0.0319	-0.9128	1.1003
MCF 10F	NM	-	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	66.7	uM	14161.189	0.0302	-0.9169	1.1003
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.000171	uM	14164.189	0.9305	0.8254	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.000853	uM	14164.189	0.8909	0.7275	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.00427	uM	14164.189	0.9475	0.8677	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.0213	uM	14164.189	0.9157	0.7885	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.107	uM	14164.189	0.6018	0.0502	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.533	uM	14164.189	0.1478	-0.8231	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	2.67	uM	14164.189	0.0128	-0.9921	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	13.3	uM	14164.189	0.0146	-0.9906	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	66.7	uM	14164.189	0.0112	-0.9933	0.7884
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.000171	uM	14637.189	0.9308	0.9478	2.7087
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.000853	uM	14637.189	0.8654	0.8960	2.7087
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.00427	uM	14637.189	0.9534	0.9651	2.7087
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.0213	uM	14637.189	0.9335	0.9499	2.7087
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.107	uM	14637.189	0.7741	0.8196	2.7087
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	0.533	uM	14637.189	0.1684	0.0361	2.7087
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	2.67	uM	14637.189	0.0149	-0.5766	2.7087
MCF12A	NM	Basal B	Z-Leu-Leu-Norvalinal	Proteasome	Proteasome	13.3	uM	14637.189	0.0091	-0.6468	2.7087

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)