Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14155.189 | 0.9638 | 0.9590 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14155.189 | 0.9321 | 0.9226 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14155.189 | 0.9590 | 0.9535 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14155.189 | 0.9361 | 0.9273 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14155.189 | 0.9788 | 0.9761 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14155.189 | 0.8557 | 0.8325 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14155.189 | 0.0433 | -0.6568 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14155.189 | 0.0130 | -0.8253 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14155.189 | 0.0117 | -0.8351 | 1.7812 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14634.189 | 0.8885 | 0.8933 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14634.189 | 0.9157 | 0.9199 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14634.189 | 0.9893 | 0.9900 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14634.189 | 0.9208 | 0.9249 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14634.189 | 0.9534 | 0.9562 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14634.189 | 0.8918 | 0.8965 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14634.189 | 0.1382 | -0.2013 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14634.189 | 0.0206 | -0.6694 | 2.1561 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14634.189 | 0.0184 | -0.6868 | 2.1561 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14209.189 | 0.9436 | 0.9431 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14209.189 | 0.9205 | 0.9193 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14209.189 | 0.9867 | 0.9867 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14209.189 | 0.9740 | 0.9739 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14209.189 | 0.9310 | 0.9302 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14209.189 | 0.7271 | 0.7070 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14209.189 | 0.0092 | -0.8057 | 2.0117 |