Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14239.189 | 0.9101 | 0.7835 | 0.8223 | |
| HCC1395 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14239.189 | 0.9640 | 0.9127 | 0.8223 | |
| HCC1395 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14239.189 | 0.9569 | 0.8957 | 0.8223 | |
| HCC1395 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14239.189 | 0.8657 | 0.6782 | 0.8223 | |
| HCC1395 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14239.189 | 0.3032 | -0.5314 | 0.8223 | |
| HCC1395 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14239.189 | 0.1562 | -0.7910 | 0.8223 | |
| HCC1395 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14239.189 | 0.5110 | -0.1162 | 0.8223 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14245.189 | 0.8893 | 0.8465 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14245.189 | 0.8933 | 0.8522 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14245.189 | 0.9204 | 0.8902 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14245.189 | 0.8999 | 0.8615 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14245.189 | 0.8749 | 0.8261 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14245.189 | 0.6385 | 0.4738 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14245.189 | 0.1767 | -0.3852 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14245.189 | 0.1678 | -0.4065 | 1.4693 | |
| HCC1569 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14245.189 | 0.1915 | -0.3507 | 1.4693 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14128.189 | 0.9407 | 0.9565 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14128.189 | 0.8709 | 0.9029 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14128.189 | 0.9453 | 0.9600 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14128.189 | 0.7981 | 0.8441 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14128.189 | 0.8997 | 0.9253 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14128.189 | 0.8774 | 0.9081 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14128.189 | 0.1614 | 0.0377 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14128.189 | 0.0161 | -0.5476 | 2.7793 | |
| HCC1806 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14128.189 | 0.0126 | -0.5853 | 2.7793 |