Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14194.189 | 0.9567 | 0.9629 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14194.189 | 0.7715 | 0.7919 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14194.189 | 0.2488 | 0.1097 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14194.189 | 0.0078 | -0.7439 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14194.189 | 0.0148 | -0.6645 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14194.189 | 0.0140 | -0.6718 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14610.189 | 1.0021 | 1.0039 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14610.189 | 0.9642 | 0.9336 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14610.189 | 0.9572 | 0.9206 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14610.189 | 0.9328 | 0.8751 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14610.189 | 0.9438 | 0.8956 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14610.189 | 0.4315 | -0.0825 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14610.189 | 0.0234 | -0.9384 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14610.189 | 0.0227 | -0.9402 | 1.0787 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14610.189 | 0.0262 | -0.9317 | 1.0787 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14197.189 | 0.9658 | 0.9494 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14197.189 | 0.9451 | 0.9187 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14197.189 | 1.0035 | 1.0051 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14197.189 | 0.9643 | 0.9472 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14197.189 | 0.9547 | 0.9329 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14197.189 | 0.9245 | 0.8878 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14197.189 | 0.2495 | -0.2798 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14197.189 | 0.0778 | -0.6943 | 1.3593 | |
| 600MPE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14197.189 | 0.1121 | -0.6004 | 1.3593 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14113.189 | 1.0113 | 1.0154 | 1.4645 |