Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7528.065 | 0.1226 | -0.6967 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7528.065 | 0.0947 | -0.7595 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 9044.065 | 0.9873 | 0.9576 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 9044.065 | 1.0544 | 1.1864 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 9044.065 | 0.9890 | 0.9632 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 9044.065 | 1.0425 | 1.1451 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 9044.065 | 0.9905 | 0.9681 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 9044.065 | 0.6816 | 0.0496 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 9044.065 | 0.5334 | -0.3052 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 9044.065 | 0.1826 | -0.8855 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 9044.065 | 0.0500 | -0.9871 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 10381.065 | 0.9920 | 0.9870 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 10381.065 | 1.0448 | 1.0720 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 10381.065 | 1.0284 | 1.0457 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 10381.065 | 1.0386 | 1.0621 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 10381.065 | 0.9875 | 0.9798 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 10381.065 | 0.7604 | 0.6034 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 10381.065 | 0.3421 | -0.1585 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 10381.065 | 0.0624 | -0.7868 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 10381.065 | 0.0353 | -0.8654 | 1.2390 | |
| SUM149PT | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7530.065 | 0.9484 | 0.9488 | 2.0424 | |
| SUM149PT | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7530.065 | 0.9690 | 0.9694 | 2.0424 | |
| SUM149PT | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7530.065 | 0.9229 | 0.9229 | 2.0424 | |
| SUM149PT | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7530.065 | 1.0137 | 1.0134 | 2.0424 | |
| SUM149PT | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7530.065 | 0.8847 | 0.8836 | 2.0424 |