Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7472.065 | 0.6811 | 0.3533 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7472.065 | 0.1191 | -0.7704 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7472.065 | 0.0882 | -0.8308 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7473.065 | 1.0051 | 1.0037 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7473.065 | 1.0949 | 1.0666 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7473.065 | 0.8653 | 0.8982 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7473.065 | 1.0451 | 1.0321 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7473.065 | 1.0648 | 1.0459 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7473.065 | 0.9769 | 0.9832 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7473.065 | 0.3059 | 0.3038 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7473.065 | 0.1019 | -0.1235 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7473.065 | 0.0110 | -0.6076 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7474.065 | 0.7642 | 0.8268 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7474.065 | 1.1108 | 1.0720 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7474.065 | 0.8487 | 0.8925 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7474.065 | 0.9477 | 0.9642 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7474.065 | 1.1536 | 1.0985 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7474.065 | 0.7197 | 0.7903 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7474.065 | 0.1484 | 0.0520 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7474.065 | 0.0359 | -0.3474 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7474.065 | 0.0084 | -0.6003 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7475.065 | 0.9439 | 0.9565 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7475.065 | 1.2082 | 1.1494 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7475.065 | 0.8753 | 0.9011 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7475.065 | 1.0522 | 1.0391 | 2.6262 |