Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 9042.018 | 0.0448 | -0.2311 | 3.2484 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 9042.018 | 0.0392 | -0.2621 | 3.2484 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9042.018 | 0.0491 | -0.2093 | 3.2484 | |
| SUM159PT | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 9042.018 | 0.0224 | -0.3788 | 3.2484 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7921.042 | 0.9685 | 0.9016 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7921.042 | 1.0599 | 1.1917 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7921.042 | 1.0382 | 1.1216 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7921.042 | 0.6115 | -0.0777 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7921.042 | 0.6079 | -0.0861 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7921.042 | 0.5273 | -0.2693 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7921.042 | 0.4313 | -0.4675 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7921.042 | 0.3171 | -0.6718 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7921.042 | 0.0437 | -0.9855 | 0.6355 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 0.000822 | uM | 9860.125 | 0.8845 | 0.8524 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 0.00411 | uM | 9860.125 | 0.4309 | 0.1818 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 0.0205 | uM | 9860.125 | 0.3190 | -0.0207 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 0.103 | uM | 9860.125 | 0.3558 | 0.0485 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 0.514 | uM | 9860.125 | 0.4144 | 0.1533 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 2.57 | uM | 9860.125 | 0.3695 | 0.0735 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 12.8 | uM | 9860.125 | 0.2861 | -0.0850 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 64.2 | uM | 9860.125 | 0.0118 | -0.8751 | 1.6001 | |
| SUM229PE | TNBC | - | Vinorelbine | TUBB | TUBB | 321 | uM | 9860.125 | 0.0102 | -0.8859 | 1.6001 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7923.018 | 0.6699 | 0.2079 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7923.018 | 0.8220 | 0.5629 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7923.018 | 0.7849 | 0.4745 | 0.7947 |