Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7905.018 | 0.1454 | -0.7659 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7905.018 | 0.1720 | -0.7178 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7905.018 | 0.2059 | -0.6554 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7905.018 | 0.3040 | -0.4682 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7905.018 | 0.1098 | -0.8287 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7906.018 | 0.5483 | 0.0324 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7906.018 | 0.3625 | -0.3454 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7906.018 | 0.1744 | -0.7074 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7906.018 | 0.1572 | -0.7389 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7906.018 | 0.1615 | -0.7311 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7906.018 | 0.1658 | -0.7233 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7906.018 | 0.3044 | -0.4599 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7906.018 | 0.0511 | -0.9241 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7906.018 | 0.2281 | -0.6069 | 0.9087 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7907.018 | 1.0747 | 1.0970 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7907.018 | 0.7569 | 0.6655 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7907.018 | 1.0751 | 1.0975 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7907.018 | 0.1050 | -0.5452 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7907.018 | 0.1469 | -0.4330 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7907.018 | 0.1513 | -0.4218 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7907.018 | 0.2121 | -0.2782 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7907.018 | 0.3043 | -0.0848 | 1.5217 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7907.018 | 0.1194 | -0.5052 | 1.5217 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7912.018 | 1.0609 | 1.1711 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7912.018 | 0.9978 | 0.9939 | 0.7203 |