Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7893.042 | 0.3975 | 0.3342 | 2.2789 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7893.042 | 0.2967 | 0.1735 | 2.2789 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7893.042 | 0.3292 | 0.2282 | 2.2789 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7893.042 | 0.3600 | 0.2774 | 2.2789 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7893.042 | 0.3684 | 0.2903 | 2.2789 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7893.042 | 0.0125 | -0.7080 | 2.2789 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7895.018 | 0.9540 | 0.9284 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7895.018 | 0.9824 | 0.9728 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7895.018 | 1.0093 | 1.0143 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7895.018 | 0.4969 | 0.1637 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7895.018 | 0.2098 | -0.4031 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7895.018 | 0.1969 | -0.4318 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7895.018 | 0.1914 | -0.4440 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7895.018 | 0.1968 | -0.4318 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7895.018 | 0.0129 | -0.9311 | 1.2916 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7896.042 | 0.4637 | 0.0330 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7896.042 | 0.4143 | -0.0623 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7896.042 | 0.3761 | -0.1372 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7896.042 | 0.3115 | -0.2663 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7896.042 | 0.3390 | -0.2110 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7896.042 | 0.3265 | -0.2359 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7896.042 | 0.3256 | -0.2378 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7896.042 | 0.4171 | -0.0569 | 1.1632 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7896.042 | 0.0113 | -0.9577 | 1.1632 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7897.018 | 0.9604 | 0.9066 | 0.8448 |