Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7865.018 | 0.2195 | -0.4395 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7865.018 | 0.1013 | -0.7070 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7865.018 | 0.0366 | -0.8752 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 9536.006 | 1.0889 | 1.1403 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 9536.006 | 0.9208 | 0.8728 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 9536.006 | 0.3276 | -0.1772 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.148 | uM | 9536.006 | 0.2700 | -0.2946 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.742 | uM | 9536.006 | 0.2687 | -0.2974 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 3.71 | uM | 9536.006 | 0.3330 | -0.1666 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 18.5 | uM | 9536.006 | 0.1119 | -0.6501 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9536.006 | 0.0144 | -0.9317 | 1.2564 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 463 | uM | 9536.006 | 0.0124 | -0.9391 | 1.2564 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7867.042 | 0.9819 | 0.9845 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7867.042 | 1.0076 | 1.0065 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7867.042 | 1.0732 | 1.0612 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7867.042 | 0.2920 | 0.1825 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7867.042 | 0.1777 | -0.0434 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7867.042 | 0.1893 | -0.0171 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7867.042 | 0.1931 | -0.0088 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7867.042 | 0.1735 | -0.0531 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7867.042 | 0.0135 | -0.6816 | 2.3427 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7868.018 | 1.0332 | 1.0312 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7868.018 | 1.0823 | 1.0763 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7868.018 | 1.0227 | 1.0214 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7868.018 | 0.9555 | 0.9573 | 2.1110 |