Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7854.018 | 0.2387 | -0.3761 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7854.018 | 0.2306 | -0.3933 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7854.018 | 0.2596 | -0.3321 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7854.018 | 0.0080 | -0.9604 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 9028.018 | 0.9770 | 0.9550 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 9028.018 | 0.9586 | 0.9192 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 9028.018 | 1.1146 | 1.2234 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 9028.018 | 0.3297 | -0.3232 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 9028.018 | 0.3323 | -0.3179 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 9028.018 | 0.2516 | -0.4801 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 9028.018 | 0.2432 | -0.4971 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9028.018 | 0.2744 | -0.4341 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 9028.018 | 0.0185 | -0.9593 | 1.0242 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000822 | uM | 9453.125 | 0.9821 | 0.9710 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00411 | uM | 9453.125 | 0.7792 | 0.6341 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0205 | uM | 9453.125 | 0.4438 | 0.0359 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.103 | uM | 9453.125 | 0.1869 | -0.4857 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.514 | uM | 9453.125 | 0.1840 | -0.4922 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 2.57 | uM | 9453.125 | 0.1917 | -0.4749 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 12.8 | uM | 9453.125 | 0.1766 | -0.5088 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 64.2 | uM | 9453.125 | 0.0092 | -0.9551 | 1.2351 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 321 | uM | 9453.125 | 0.0104 | -0.9503 | 1.2351 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7856.018 | 1.0593 | 1.1265 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7856.018 | 0.9616 | 0.9183 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7856.018 | 1.1105 | 1.2361 | 0.9388 |