Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7824.018 | 0.5355 | 0.2423 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7824.018 | 0.2930 | -0.2156 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7824.018 | 0.0179 | -0.9069 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7825.018 | 0.9550 | 0.9539 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7825.018 | 0.9314 | 0.9293 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7825.018 | 0.7447 | 0.7226 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7825.018 | 0.4972 | 0.4037 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7825.018 | 0.5489 | 0.4760 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7825.018 | 0.4858 | 0.3874 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7825.018 | 0.4140 | 0.2795 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7825.018 | 0.2233 | -0.0642 | 1.9741 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7825.018 | 0.0139 | -0.7704 | 1.9741 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7829.042 | 0.9886 | 0.9877 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7829.042 | 0.9651 | 0.9623 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7829.042 | 0.9328 | 0.9269 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7829.042 | 0.0983 | -0.4226 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7829.042 | 0.0788 | -0.4871 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7829.042 | 0.0790 | -0.4864 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7829.042 | 0.0929 | -0.4396 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7829.042 | 0.1166 | -0.3673 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7829.042 | 0.0144 | -0.7934 | 1.8673 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7830.018 | 1.2513 | 1.3152 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7830.018 | 1.3006 | 1.3743 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7830.018 | 1.1909 | 1.2416 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7830.018 | 0.9209 | 0.8953 | 1.5320 |