Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7793.018 | 0.0609 | -0.7604 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7793.018 | 0.0809 | -0.7028 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7793.018 | 0.0878 | -0.6839 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7793.018 | 0.1156 | -0.6105 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7793.018 | 0.0240 | -0.8816 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7794.018 | 1.4325 | 1.4767 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7794.018 | 1.3667 | 1.4084 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7794.018 | 1.3242 | 1.3636 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7794.018 | 1.2907 | 1.3278 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7794.018 | 0.0632 | -0.6131 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7794.018 | 0.1351 | -0.3920 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7794.018 | 0.1641 | -0.3174 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7794.018 | 0.1761 | -0.2882 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7794.018 | 0.0478 | -0.6721 | 1.6812 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 9035.018 | 0.9321 | 0.9358 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 9035.018 | 1.0948 | 1.0859 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 9035.018 | 0.9183 | 0.9225 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 9035.018 | 0.0873 | -0.3549 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 9035.018 | 0.0614 | -0.4521 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 9035.018 | 0.0989 | -0.3164 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 9035.018 | 0.1227 | -0.2442 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9035.018 | 0.1244 | -0.2396 | 2.1555 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 9035.018 | 0.0693 | -0.4202 | 2.1555 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7798.018 | 0.9984 | 0.9978 | 1.4461 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7798.018 | 1.0195 | 1.0269 | 1.4461 |