Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7787.018 | 0.9378 | 0.6883 | 0.3791 | |
| 184A1 | NM | Basal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7787.018 | 0.8848 | 0.4481 | 0.3791 | |
| 184A1 | NM | Basal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7787.018 | 0.0920 | -0.9963 | 0.3791 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7791.018 | 1.0436 | 1.1022 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7791.018 | 0.9842 | 0.9632 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7791.018 | 1.1171 | 1.2762 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7791.018 | 0.8371 | 0.6248 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7791.018 | 0.6159 | 0.1351 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7791.018 | 0.5920 | 0.0838 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7791.018 | 0.6308 | 0.1673 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7791.018 | 0.7449 | 0.4177 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7791.018 | 0.0140 | -0.9863 | 0.8558 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 9118.006 | 0.9829 | 0.9691 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 9118.006 | 1.0022 | 1.0040 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 9118.006 | 0.6448 | 0.3463 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.148 | uM | 9118.006 | 0.7290 | 0.5040 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.742 | uM | 9118.006 | 0.7272 | 0.5005 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 3.71 | uM | 9118.006 | 0.8155 | 0.6639 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 18.5 | uM | 9118.006 | 0.5996 | 0.2609 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9118.006 | 0.0070 | -0.9773 | 1.1089 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 463 | uM | 9118.006 | 0.0085 | -0.9730 | 1.1089 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7793.018 | 1.0029 | 1.0044 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7793.018 | 0.9418 | 0.9111 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7793.018 | 0.9984 | 0.9976 | 1.3186 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7793.018 | 0.0458 | -0.8072 | 1.3186 |