Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 24 | uM | 10874.143 | 0.9771 | 0.9402 | 0.7639 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 120 | uM | 10874.143 | 1.0024 | 1.0062 | 0.7639 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 600 | uM | 10874.143 | 0.8759 | 0.6815 | 0.7639 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 3000 | uM | 10874.143 | 0.3131 | -0.5626 | 0.7639 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 15000 | uM | 10874.143 | 0.0141 | -0.9925 | 0.7639 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12220.143 | 0.9238 | 0.6790 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 0.192 | uM | 12220.143 | 0.9257 | 0.6866 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 0.96 | uM | 12220.143 | 0.9131 | 0.6365 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 4.8 | uM | 12220.143 | 0.9597 | 0.8264 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 24 | uM | 12220.143 | 0.8190 | 0.2874 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 120 | uM | 12220.143 | 0.8308 | 0.3286 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 600 | uM | 12220.143 | 0.6163 | -0.3127 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 3000 | uM | 12220.143 | 0.2518 | -0.9047 | 0.4532 | |
| MX1 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 15000 | uM | 12220.143 | 0.0193 | -0.9997 | 0.4532 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.0384 | uM | 11851.143 | 0.8713 | 0.8181 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.192 | uM | 11851.143 | 0.9605 | 0.9450 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.96 | uM | 11851.143 | 0.9162 | 0.8824 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 4.8 | uM | 11851.143 | 0.9823 | 0.9754 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 24 | uM | 11851.143 | 0.9165 | 0.8829 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 120 | uM | 11851.143 | 0.8855 | 0.8386 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 600 | uM | 11851.143 | 0.7867 | 0.6940 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 3000 | uM | 11851.143 | 0.2490 | -0.2361 | 1.4447 | |
| SK-BR-3 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 15000 | uM | 11851.143 | 0.0146 | -0.8929 | 1.4447 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10875.143 | 1.0020 | 1.0050 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 10875.143 | 0.9926 | 0.9821 | 0.8219 |