Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7430.065 | 1.0537 | 1.0551 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7430.065 | 0.9580 | 0.9559 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7430.065 | 1.0594 | 1.0608 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7430.065 | 0.9582 | 0.9561 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 8 | uM | 7430.065 | 0.8865 | 0.8788 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 40 | uM | 7430.065 | 0.1957 | -0.1425 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 200 | uM | 7430.065 | 0.1241 | -0.3230 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1000 | uM | 7430.065 | 0.1145 | -0.3508 | 1.9263 | |
| HCC1143 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 5000 | uM | 7430.065 | 0.0480 | -0.5867 | 1.9263 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7431.065 | 1.0984 | 1.1323 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7431.065 | 1.0395 | 1.0536 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7431.065 | 1.1071 | 1.1439 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7431.065 | 0.9769 | 0.9683 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 8 | uM | 7431.065 | 0.3847 | 0.0419 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 40 | uM | 7431.065 | 0.0302 | -0.8164 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 200 | uM | 7431.065 | 0.0163 | -0.8796 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1000 | uM | 7431.065 | 0.0150 | -0.8862 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 5000 | uM | 7431.065 | 0.0183 | -0.8695 | 1.4650 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7432.065 | 1.1211 | 1.3081 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7432.065 | 1.1073 | 1.2723 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7432.065 | 1.1349 | 1.3437 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7432.065 | 0.8420 | 0.6123 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 8 | uM | 7432.065 | 0.1199 | -0.8597 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 40 | uM | 7432.065 | 0.0228 | -0.9825 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 200 | uM | 7432.065 | 0.0109 | -0.9930 | 0.7981 |