Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.288 | uM | 7487.102 | 0.8359 | 0.7785 | 1.5273 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 1.44 | uM | 7487.102 | 0.9229 | 0.8977 | 1.5273 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 7.2 | uM | 7487.102 | 0.5853 | 0.4084 | 1.5273 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.0000184 | uM | 9566.026 | 1.0068 | 1.0064 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.0000922 | uM | 9566.026 | 1.2448 | 1.2158 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.000461 | uM | 9566.026 | 1.0144 | 1.0134 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.0023 | uM | 9566.026 | 1.3978 | 1.3394 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.0115 | uM | 9566.026 | 1.0350 | 1.0324 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.0576 | uM | 9566.026 | 1.2583 | 1.2270 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 0.288 | uM | 9566.026 | 1.0134 | 1.0125 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 1.44 | uM | 9566.026 | 0.9662 | 0.9681 | 2.1367 | |
| MCF 10F | NM | - | Trastuzumab | HER2 | ErbB | 7.2 | uM | 9566.026 | 1.0144 | 1.0134 | 2.1367 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0000184 | uM | 7489.102 | 0.9830 | 0.9859 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0000922 | uM | 7489.102 | 1.0122 | 1.0101 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.000461 | uM | 7489.102 | 0.9911 | 0.9926 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0023 | uM | 7489.102 | 0.9995 | 0.9996 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0115 | uM | 7489.102 | 0.9653 | 0.9710 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0576 | uM | 7489.102 | 0.9593 | 0.9660 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.288 | uM | 7489.102 | 0.9086 | 0.9224 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 1.44 | uM | 7489.102 | 0.9757 | 0.9798 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 7.2 | uM | 7489.102 | 0.8034 | 0.8273 | 2.4234 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0000184 | uM | 10061.123 | 1.0334 | 1.0348 | 1.9064 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0000922 | uM | 10061.123 | 0.9820 | 0.9810 | 1.9064 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.000461 | uM | 10061.123 | 1.0228 | 1.0238 | 1.9064 | |
| MCF12A | NM | Basal B | Trastuzumab | HER2 | ErbB | 0.0023 | uM | 10061.123 | 1.0494 | 1.0512 | 1.9064 |