Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Torkinib | 0.4 | uM | 15394.211 | 0.2262 | -0.1123 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Torkinib | 2 | uM | 15394.211 | 0.2055 | -0.1577 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Torkinib | 10 | uM | 15394.211 | 0.1936 | -0.1846 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Torkinib | 50 | uM | 15394.211 | 0.1697 | -0.2414 | 1.8299 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 0.000128 | uM | 15355.211 | 0.8204 | 0.6589 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 0.00064 | uM | 15355.211 | 0.6720 | 0.3738 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 0.0032 | uM | 15355.211 | 0.5270 | 0.0920 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 0.016 | uM | 15355.211 | 0.4226 | -0.1137 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 0.08 | uM | 15355.211 | 0.3522 | -0.2538 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 0.4 | uM | 15355.211 | 0.2602 | -0.4394 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 2 | uM | 15355.211 | 0.1989 | -0.5651 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 10 | uM | 15355.211 | 0.1683 | -0.6286 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Torkinib | 50 | uM | 15355.211 | 0.0783 | -0.8198 | 1.0584 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 0.000128 | uM | 15321.211 | 0.8648 | 0.8969 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 0.00064 | uM | 15321.211 | 0.7335 | 0.7864 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 0.0032 | uM | 15321.211 | 0.6957 | 0.7523 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 0.016 | uM | 15321.211 | 0.5382 | 0.5957 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 0.08 | uM | 15321.211 | 0.4082 | 0.4428 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 0.4 | uM | 15321.211 | 0.2494 | 0.2056 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 2 | uM | 15321.211 | 0.1015 | -0.1313 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 10 | uM | 15321.211 | 0.0377 | -0.3944 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Torkinib | 50 | uM | 15321.211 | 0.0226 | -0.4972 | 2.7437 | |||
| MDA-MB-361 | HER2amp | Luminal | Torkinib | 0.000128 | uM | 15396.211 | 0.9577 | 0.9075 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Torkinib | 0.00064 | uM | 15396.211 | 0.8876 | 0.7554 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Torkinib | 0.0032 | uM | 15396.211 | 0.7806 | 0.5252 | 0.9137 |