Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.000427	uM	7533.069	0.9187	0.8602	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.00213	uM	7533.069	0.7808	0.6191	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.0107	uM	7533.069	0.6444	0.3743	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.0533	uM	7533.069	0.6360	0.3591	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.267	uM	7533.069	0.6013	0.2954	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	1.33	uM	7533.069	0.6211	0.3318	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	6.67	uM	7533.069	0.6120	0.3151	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	33.3	uM	7533.069	0.6002	0.2934	1.1713
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.0000853	uM	7534.069	0.9757	0.9438	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.000427	uM	7534.069	0.9163	0.8075	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.00213	uM	7534.069	0.8650	0.6910	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.0107	uM	7534.069	0.7079	0.3408	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.0533	uM	7534.069	0.6768	0.2730	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	0.267	uM	7534.069	0.6436	0.2011	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	1.33	uM	7534.069	0.6554	0.2266	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	6.67	uM	7534.069	0.6232	0.1571	0.8641
SUM225CWN	HER2amp	Basal A	Sirolimus	MTOR	MTOR	33.3	uM	7534.069	0.1297	-0.8119	0.8641
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	0.000427	uM	7536.068	0.9865	0.9579	0.6416
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	0.00213	uM	7536.068	1.0725	1.2306	0.6416
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	0.0107	uM	7536.068	0.8835	0.6490	0.6416
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	0.0533	uM	7536.068	0.8316	0.5004	0.6416
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	0.267	uM	7536.068	0.9339	0.7977	0.6416
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	1.33	uM	7536.068	0.8394	0.5224	0.6416
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	6.67	uM	7536.068	0.9602	0.8773	0.6416
SUM229PE	TNBC	-	Sirolimus	MTOR	MTOR	33.3	uM	7536.068	0.4066	-0.5080	0.6416

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)