Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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EFM-192A | HER2amp | Luminal | Ribavirin | 50 | uM | 15284.211 | 0.9192 | 0.8208 | 0.8976 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.000128 | uM | 15288.211 | 0.9940 | 0.9870 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.00064 | uM | 15288.211 | 0.9534 | 0.8994 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.0032 | uM | 15288.211 | 0.9935 | 0.9860 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.016 | uM | 15288.211 | 0.9525 | 0.8975 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.08 | uM | 15288.211 | 1.0415 | 1.0899 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.4 | uM | 15288.211 | 1.0621 | 1.1345 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 2 | uM | 15288.211 | 1.0489 | 1.1059 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 10 | uM | 15288.211 | 1.1601 | 1.3483 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 50 | uM | 15288.211 | 1.0722 | 1.1566 | 0.9250 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.000128 | uM | 15387.211 | 0.9976 | 0.9961 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.00064 | uM | 15387.211 | 0.9661 | 0.9451 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.0032 | uM | 15387.211 | 0.9996 | 0.9993 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.016 | uM | 15387.211 | 0.9413 | 0.9048 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.08 | uM | 15387.211 | 1.0099 | 1.0159 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 0.4 | uM | 15387.211 | 1.0799 | 1.1279 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 2 | uM | 15387.211 | 1.1419 | 1.2259 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 10 | uM | 15387.211 | 1.1777 | 1.2819 | 1.2404 | |||
EFM-192B | HER2amp | Luminal | Ribavirin | 50 | uM | 15387.211 | 1.0384 | 1.0617 | 1.2404 | |||
EFM-192C | HER2amp | Luminal | Ribavirin | 0.000128 | uM | 15292.211 | 1.0624 | 1.0695 | 1.7715 | |||
EFM-192C | HER2amp | Luminal | Ribavirin | 0.00064 | uM | 15292.211 | 0.6586 | 0.5799 | 1.7715 | |||
EFM-192C | HER2amp | Luminal | Ribavirin | 0.0032 | uM | 15292.211 | 0.8711 | 0.8501 | 1.7715 | |||
EFM-192C | HER2amp | Luminal | Ribavirin | 0.016 | uM | 15292.211 | 0.7631 | 0.7169 | 1.7715 | |||
EFM-192C | HER2amp | Luminal | Ribavirin | 0.08 | uM | 15292.211 | 0.9352 | 0.9258 | 1.7715 | |||
EFM-192C | HER2amp | Luminal | Ribavirin | 0.4 | uM | 15292.211 | 1.0878 | 1.0973 | 1.7715 |