Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.0064 | uM | 10580.136 | 0.9150 | 0.7681 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.032 | uM | 10580.136 | 0.9278 | 0.8024 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.16 | uM | 10580.136 | 0.9279 | 0.8028 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.8 | uM | 10580.136 | 0.9425 | 0.8422 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 4 | uM | 10580.136 | 0.9645 | 0.9021 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 20 | uM | 10580.136 | 0.8823 | 0.6809 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 100 | uM | 10580.136 | 0.7044 | 0.2297 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.000128 | uM | 10754.152 | 0.9425 | 0.8920 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.00064 | uM | 10754.152 | 0.9129 | 0.8363 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.0032 | uM | 10754.152 | 0.9699 | 0.9436 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.016 | uM | 10754.152 | 0.9865 | 0.9747 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.08 | uM | 10754.152 | 1.0259 | 1.0485 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.4 | uM | 10754.152 | 0.8969 | 0.8060 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 2 | uM | 10754.152 | 0.9088 | 0.8285 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 10 | uM | 10754.152 | 0.8352 | 0.6894 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 50 | uM | 10754.152 | 0.8233 | 0.6668 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.000256 | uM | 11938.159 | 0.9612 | 0.8211 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.00128 | uM | 11938.159 | 0.9885 | 0.9459 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.0064 | uM | 11938.159 | 1.0141 | 1.0675 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.032 | uM | 11938.159 | 0.9951 | 0.9766 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.16 | uM | 11938.159 | 1.0243 | 1.1169 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.8 | uM | 11938.159 | 1.0174 | 1.0833 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 4 | uM | 11938.159 | 1.0069 | 1.0329 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 20 | uM | 11938.159 | 0.9005 | 0.5599 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 100 | uM | 11938.159 | 0.8225 | 0.2584 | 0.4219 |