Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12224.152 | 1.0095 | 1.0176 | 1.0761 | |
| 600MPE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12224.152 | 0.0586 | -0.8567 | 1.0761 | |
| 600MPE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12224.152 | 0.0135 | -0.9633 | 1.0761 | |
| 600MPE | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12224.152 | 0.0122 | -0.9666 | 1.0761 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10880.152 | 0.9703 | 0.9602 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10880.152 | 1.0126 | 1.0167 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10880.152 | 0.9990 | 0.9987 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10880.152 | 1.0404 | 1.0534 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10880.152 | 0.9631 | 0.9505 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10880.152 | 0.7181 | 0.6042 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10880.152 | 0.1164 | -0.5225 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10880.152 | 0.0162 | -0.8714 | 1.5019 | |
| AU565 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10880.152 | 0.0093 | -0.9114 | 1.5019 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10581.14 | 0.9451 | 0.8855 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10581.14 | 0.9325 | 0.8591 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10581.14 | 0.9273 | 0.8482 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10581.14 | 0.9805 | 0.9593 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10581.14 | 0.9537 | 0.9033 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10581.14 | 0.8568 | 0.7017 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10581.14 | 0.4767 | -0.0779 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10581.14 | 0.0106 | -0.9828 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10581.14 | 0.0101 | -0.9836 | 0.9569 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11854.159 | 0.9547 | 0.9279 | 1.2639 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11854.159 | 0.9659 | 0.9458 | 1.2639 | |
| BT-20 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11854.159 | 0.9995 | 0.9992 | 1.2639 |