Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11057.145 | 0.0004 | -0.7373 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14176.189 | 1.1536 | 1.7918 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14176.189 | 1.1536 | 1.7918 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14176.189 | 1.0344 | 1.1645 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14176.189 | 1.0344 | 1.1645 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14176.189 | 1.4330 | 3.6310 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14176.189 | 1.4330 | 3.6310 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14176.189 | 1.9005 | 7.9498 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14176.189 | 1.9005 | 7.9498 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14176.189 | 0.6419 | -0.2893 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14176.189 | 0.6419 | -0.2893 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14176.189 | 0.0016 | -1.0000 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14176.189 | 0.0016 | -1.0000 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14176.189 | 0.0066 | -1.0000 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14176.189 | 0.0066 | -1.0000 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14176.189 | 0.0016 | -1.0000 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14176.189 | 0.0016 | -1.0000 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14176.189 | 0.7463 | 0.0103 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14176.189 | 0.7463 | 0.0103 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14287.189 | 0.9784 | 0.9818 | 2.3947 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14287.189 | 0.9784 | 0.9818 | 2.3947 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14287.189 | 0.9757 | 0.9796 | 2.3947 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14287.189 | 0.9757 | 0.9796 | 2.3947 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14287.189 | 1.0904 | 1.0736 | 2.3947 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14287.189 | 1.0904 | 1.0736 | 2.3947 |