Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11850.145 | 0.9776 | 0.9790 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11850.145 | 0.9776 | 0.9790 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11850.145 | 0.9765 | 0.9780 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11850.145 | 0.9765 | 0.9780 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11850.145 | 0.9289 | 0.9325 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11850.145 | 0.9289 | 0.9325 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11850.145 | 1.0102 | 1.0095 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11850.145 | 1.0102 | 1.0095 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11850.145 | 0.9050 | 0.9092 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11850.145 | 0.9050 | 0.9092 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11850.145 | 0.0236 | -0.6501 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11850.145 | 0.0236 | -0.6501 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11850.145 | 0.0113 | -0.7518 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11850.145 | 0.0113 | -0.7518 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11850.145 | 0.0133 | -0.7324 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11850.145 | 0.0133 | -0.7324 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11850.145 | 0.0106 | -0.7584 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11850.145 | 0.0106 | -0.7584 | 2.1492 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14212.189 | 0.9504 | 0.9384 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14212.189 | 0.9504 | 0.9384 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14212.189 | 0.9481 | 0.9354 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14212.189 | 0.9481 | 0.9354 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14212.189 | 0.9370 | 0.9215 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14212.189 | 0.9370 | 0.9215 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14212.189 | 0.9550 | 0.9442 | 1.6254 |