Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13635.184 | 0.1056 | -0.5504 | 1.5062 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13635.184 | 0.0462 | -0.7403 | 1.5062 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13635.184 | 1.0144 | 1.0191 | 1.5062 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 0.138 | uM | 13607.184 | 0.9656 | 0.9202 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 0.691 | uM | 13607.184 | 0.9221 | 0.8203 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 3.46 | uM | 13607.184 | 0.9226 | 0.8213 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 17.3 | uM | 13607.184 | 0.9151 | 0.8042 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 86.4 | uM | 13607.184 | 0.8437 | 0.6418 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 432 | uM | 13607.184 | 0.9336 | 0.8465 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 2160 | uM | 13607.184 | 0.1346 | -0.8052 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 10800 | uM | 13607.184 | 0.1897 | -0.7097 | 0.8612 | |||
| HCC70 | TNBC | Basal A | Methylglyoxal | 54000 | uM | 13607.184 | 0.9044 | 0.7797 | 0.8612 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13504.184 | 1.0432 | 1.0430 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13504.184 | 1.0699 | 1.0692 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13504.184 | 0.9843 | 0.9842 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13504.184 | 0.6117 | 0.5620 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13504.184 | 0.9466 | 0.9456 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 432 | uM | 13504.184 | 0.4251 | 0.3008 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13504.184 | 0.0023 | -0.9053 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13504.184 | 0.0009 | -0.9422 | 1.9883 | |||
| Hs 578T | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13504.184 | 0.0009 | -0.9422 | 1.9883 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13639.184 | 0.9989 | 0.9986 | 1.5976 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13639.184 | 0.9915 | 0.9893 | 1.5976 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13639.184 | 0.9794 | 0.9741 | 1.5976 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13639.184 | 0.9939 | 0.9923 | 1.5976 |