Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Methylglyoxal | 54000 | uM | 13177.184 | 0.0006 | -1.0000 | 0.3394 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 0.138 | uM | 13631.184 | 1.1067 | 1.1550 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 0.691 | uM | 13631.184 | 1.0143 | 1.0210 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 3.46 | uM | 13631.184 | 0.8528 | 0.7786 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 17.3 | uM | 13631.184 | 0.6431 | 0.4449 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 86.4 | uM | 13631.184 | 0.8032 | 0.7019 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 432 | uM | 13631.184 | 0.5241 | 0.2428 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 2160 | uM | 13631.184 | 0.0300 | -0.8488 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 10800 | uM | 13631.184 | 0.0042 | -0.9647 | 1.3577 | |||
| HCC1954 | HER2amp | Basal A | Methylglyoxal | 54000 | uM | 13631.184 | 1.0552 | 1.0808 | 1.3577 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 0.138 | uM | 13603.184 | 0.9412 | 0.8437 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 0.691 | uM | 13603.184 | 0.9312 | 0.8174 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 3.46 | uM | 13603.184 | 0.9217 | 0.7927 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 17.3 | uM | 13603.184 | 0.7347 | 0.3222 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 86.4 | uM | 13603.184 | 0.7661 | 0.3987 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 432 | uM | 13603.184 | 0.6542 | 0.1317 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 2160 | uM | 13603.184 | 0.0119 | -0.9948 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 10800 | uM | 13603.184 | 0.0121 | -0.9947 | 0.7451 | |||
| HCC3153 | TNBC | Basal A | Methylglyoxal | 54000 | uM | 13603.184 | 0.1169 | -0.8879 | 0.7451 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13635.184 | 0.9862 | 0.9817 | 1.5062 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13635.184 | 1.0533 | 1.0702 | 1.5062 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13635.184 | 1.0332 | 1.0438 | 1.5062 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13635.184 | 0.9323 | 0.9091 | 1.5062 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13635.184 | 0.9954 | 0.9938 | 1.5062 | |||
| HCC38 | TNBC | Basal B | Methylglyoxal | 432 | uM | 13635.184 | 0.8121 | 0.7419 | 1.5062 |