Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.00213 | uM | 10996.154 | 0.9753 | 0.9067 | 0.5230 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.0107 | uM | 10996.154 | 1.0296 | 1.1147 | 0.5230 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.0533 | uM | 10996.154 | 0.8936 | 0.6130 | 0.5230 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.267 | uM | 10996.154 | 0.1648 | -0.9363 | 0.5230 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 1.33 | uM | 10996.154 | 0.0117 | -0.9996 | 0.5230 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 6.67 | uM | 10996.154 | 0.0160 | -0.9993 | 0.5230 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 33.3 | uM | 10996.154 | 0.0192 | -0.9990 | 0.5230 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.0000853 | uM | 12192.154 | 0.9605 | 0.8554 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.000427 | uM | 12192.154 | 1.0103 | 1.0384 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.00213 | uM | 12192.154 | 1.0234 | 1.0879 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.0107 | uM | 12192.154 | 1.0725 | 1.2779 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.0533 | uM | 12192.154 | 0.8928 | 0.6199 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 0.267 | uM | 12192.154 | 0.1683 | -0.9273 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 1.33 | uM | 12192.154 | 0.0134 | -0.9993 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 6.67 | uM | 12192.154 | 0.0156 | -0.9991 | 0.5377 | |
| HCC2185 | TNBC | Luminal | LBH589 | HDAC | HDAC | 33.3 | uM | 12192.154 | 0.0176 | -0.9989 | 0.5377 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.0000853 | uM | 10937.154 | 0.9780 | 0.9711 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.000427 | uM | 10937.154 | 0.9267 | 0.9028 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.00213 | uM | 10937.154 | 1.0096 | 1.0125 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.0107 | uM | 10937.154 | 1.0212 | 1.0276 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.0533 | uM | 10937.154 | 0.9834 | 0.9782 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.267 | uM | 10937.154 | 0.6808 | 0.5554 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 1.33 | uM | 10937.154 | 0.1974 | -0.3078 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 6.67 | uM | 10937.154 | 0.1402 | -0.4467 | 1.5291 | |
| HCC3153 | TNBC | Basal A | LBH589 | HDAC | HDAC | 33.3 | uM | 10937.154 | 0.1013 | -0.5527 | 1.5291 |