Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.000427 | uM | 10753.154 | 1.0394 | 1.0543 | 1.4444 | |
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.00213 | uM | 10753.154 | 1.0467 | 1.0642 | 1.4444 | |
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.0107 | uM | 10753.154 | 1.1042 | 1.1421 | 1.4444 | |
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.0533 | uM | 10753.154 | 1.0277 | 1.0382 | 1.4444 | |
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 0.267 | uM | 10753.154 | 0.2807 | -0.1701 | 1.4444 | |
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 1.33 | uM | 10753.154 | 0.0483 | -0.7545 | 1.4444 | |
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 6.67 | uM | 10753.154 | 0.0271 | -0.8357 | 1.4444 | |
| HCC1187 | TNBC | Basal A | LBH589 | HDAC | HDAC | 33.3 | uM | 10753.154 | 0.0217 | -0.8590 | 1.4444 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0000853 | uM | 12000.167 | 0.9765 | 0.9350 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.000427 | uM | 12000.167 | 0.9657 | 0.9051 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.00213 | uM | 12000.167 | 1.0059 | 1.0164 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0107 | uM | 12000.167 | 1.0084 | 1.0233 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0533 | uM | 12000.167 | 0.9682 | 0.9119 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.267 | uM | 12000.167 | 0.8067 | 0.4832 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 1.33 | uM | 12000.167 | 0.2412 | -0.7237 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 6.67 | uM | 12000.167 | 0.2031 | -0.7825 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 33.3 | uM | 12000.167 | 0.1159 | -0.9003 | 0.7185 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0000853 | uM | 12084.154 | 0.9833 | 0.9741 | 1.2963 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.000427 | uM | 12084.154 | 0.9399 | 0.9067 | 1.2963 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.00213 | uM | 12084.154 | 1.0635 | 1.0973 | 1.2963 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0107 | uM | 12084.154 | 0.9642 | 0.9445 | 1.2963 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.0533 | uM | 12084.154 | 0.9295 | 0.8904 | 1.2963 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 0.267 | uM | 12084.154 | 0.7118 | 0.5387 | 1.2963 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 1.33 | uM | 12084.154 | 0.2850 | -0.2405 | 1.2963 | |
| HCC1395 | TNBC | Basal B | LBH589 | HDAC | HDAC | 6.67 | uM | 12084.154 | 0.1741 | -0.4807 | 1.2963 |