Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.0107 | uM | 10644.137 | 0.9685 | 0.8931 | 0.5827 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.0533 | uM | 10644.137 | 1.0309 | 1.1073 | 0.5827 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.267 | uM | 10644.137 | 0.9962 | 0.9869 | 0.5827 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 1.33 | uM | 10644.137 | 0.9938 | 0.9787 | 0.5827 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 6.67 | uM | 10644.137 | 0.8186 | 0.4185 | 0.5827 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 33.3 | uM | 10644.137 | 0.0437 | -0.9907 | 0.5827 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.0000853 | uM | 10874.149 | 0.9885 | 0.9722 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.000427 | uM | 10874.149 | 1.0881 | 1.2159 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.00213 | uM | 10874.149 | 0.9949 | 0.9877 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.0107 | uM | 10874.149 | 1.0481 | 1.1174 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.0533 | uM | 10874.149 | 0.9843 | 0.9619 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.267 | uM | 10874.149 | 1.0228 | 1.0555 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 1.33 | uM | 10874.149 | 0.9164 | 0.7988 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 6.67 | uM | 10874.149 | 1.0031 | 1.0075 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 33.3 | uM | 10874.149 | 0.2338 | -0.6573 | 0.8239 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.000128 | uM | 12220.161 | 0.8924 | 0.5685 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.00064 | uM | 12220.161 | 1.0849 | 1.3800 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.0032 | uM | 12220.161 | 1.0370 | 1.1614 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.016 | uM | 12220.161 | 1.1269 | 1.5813 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.08 | uM | 12220.161 | 1.0208 | 1.0900 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 0.4 | uM | 12220.161 | 0.9809 | 0.9191 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 2 | uM | 12220.161 | 1.0279 | 1.1212 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 10 | uM | 12220.161 | 0.9009 | 0.6005 | 0.4684 | |
| MX1 | Unknown | Unknown | L-779450 | BRAF | MAPK | 50 | uM | 12220.161 | 0.0693 | -0.9933 | 0.4684 | |
| SK-BR-3 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.000128 | uM | 11851.161 | 0.9753 | 0.9659 | 1.4516 |