Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7547.095 | 0.6245 | 0.2550 | 1.0102 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7547.095 | 0.6071 | 0.2204 | 1.0102 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7547.095 | 0.6961 | 0.3972 | 1.0102 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7547.095 | 0.6868 | 0.3789 | 1.0102 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7547.095 | 0.0083 | -0.9827 | 1.0102 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 10420.095 | 1.0554 | 1.1955 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 10420.095 | 1.0167 | 1.0582 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 10420.095 | 0.8987 | 0.6627 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 10420.095 | 0.7125 | 0.1130 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 10420.095 | 0.7049 | 0.0925 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 10420.095 | 0.6964 | 0.0699 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 10420.095 | 0.7463 | 0.2059 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 10420.095 | 0.8291 | 0.4464 | 0.5783 | |
| UACC-812 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 10420.095 | 0.0103 | -0.9993 | 0.5783 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7552.095 | 0.9771 | 0.9587 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7552.095 | 0.9283 | 0.8704 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7552.095 | 0.9926 | 0.9867 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7552.095 | 1.0020 | 1.0035 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7552.095 | 0.9728 | 0.9510 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7552.095 | 0.8419 | 0.7130 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7552.095 | 0.2052 | -0.5195 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7552.095 | 0.0120 | -0.9627 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7552.095 | 0.0082 | -0.9734 | 1.1106 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7553.095 | 0.9803 | 0.9656 | 1.1473 | |
| ZR-75-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7553.095 | 0.9431 | 0.9005 | 1.1473 |