Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7431.095 | 1.0084 | 1.0131 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7431.095 | 0.9764 | 0.9629 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7431.095 | 0.1965 | -0.4403 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7431.095 | 0.0135 | -0.9312 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7431.095 | 0.0170 | -0.9174 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7431.095 | 0.0161 | -0.9211 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7431.095 | 0.0123 | -0.9361 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7431.095 | 0.0092 | -0.9491 | 1.2776 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7432.095 | 1.0361 | 1.0866 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7432.095 | 0.9401 | 0.8577 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7432.095 | 0.2462 | -0.6255 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7432.095 | 0.0514 | -0.9424 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7432.095 | 0.0505 | -0.9436 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7432.095 | 0.0627 | -0.9269 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7432.095 | 0.0539 | -0.9390 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7432.095 | 0.0097 | -0.9922 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7432.095 | 0.0132 | -0.9887 | 0.8368 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7433.095 | 1.0647 | 1.1400 | 0.9260 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7433.095 | 1.0501 | 1.1085 | 0.9260 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7433.095 | 0.4891 | -0.0761 | 0.9260 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7433.095 | 0.0562 | -0.9107 | 0.9260 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7433.095 | 0.0399 | -0.9382 | 0.9260 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7433.095 | 0.0418 | -0.9352 | 0.9260 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7433.095 | 0.0496 | -0.9219 | 0.9260 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7433.095 | 0.0067 | -0.9910 | 0.9260 |