Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7495.067 | 0.9777 | 0.9604 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7495.067 | 1.0366 | 1.0649 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7495.067 | 0.8346 | 0.7036 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7495.067 | 0.3194 | -0.2732 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.267 | uM | 7495.067 | 0.2948 | -0.3230 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 1.33 | uM | 7495.067 | 0.3046 | -0.3031 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 6.67 | uM | 7495.067 | 0.1923 | -0.5366 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 33.3 | uM | 7495.067 | 0.0010 | -0.9958 | 1.1275 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 7496.067 | 1.0502 | 1.0886 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7496.067 | 0.9759 | 0.9573 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7496.067 | 0.9686 | 0.9443 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7496.067 | 0.9816 | 0.9674 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7496.067 | 0.3591 | -0.1920 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.267 | uM | 7496.067 | 0.2986 | -0.3136 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 1.33 | uM | 7496.067 | 0.3130 | -0.2845 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 6.67 | uM | 7496.067 | 0.2213 | -0.4734 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 33.3 | uM | 7496.067 | 0.0044 | -0.9834 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 7498.067 | 1.0192 | 1.0338 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7498.067 | 0.9660 | 0.9400 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7498.067 | 0.9794 | 0.9636 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7498.067 | 0.9949 | 0.9910 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7498.067 | 0.3889 | -0.1299 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.267 | uM | 7498.067 | 0.2697 | -0.3699 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 1.33 | uM | 7498.067 | 0.2892 | -0.3299 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Ispinesib | KSP | Kinesin | 6.67 | uM | 7498.067 | 0.2041 | -0.5070 | 1.1346 |