Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7473.067 | 0.9846 | 0.9884 | 2.6736 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7473.067 | 1.1750 | 1.1244 | 2.6736 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7473.067 | 0.5496 | 0.5988 | 2.6736 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.267 | uM | 7473.067 | 0.4812 | 0.5213 | 2.6736 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 1.33 | uM | 7473.067 | 0.4820 | 0.5223 | 2.6736 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 6.67 | uM | 7473.067 | 0.2722 | 0.2294 | 2.6736 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 33.3 | uM | 7473.067 | 0.0005 | -0.8838 | 2.6736 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 7474.067 | 1.4169 | 1.2708 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7474.067 | 1.0490 | 1.0352 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7474.067 | 1.1156 | 1.0813 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7474.067 | 1.1818 | 1.1255 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7474.067 | 0.4257 | 0.4651 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.267 | uM | 7474.067 | 0.3150 | 0.3129 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 1.33 | uM | 7474.067 | 0.3366 | 0.3450 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 6.67 | uM | 7474.067 | 0.2556 | 0.2166 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 33.3 | uM | 7474.067 | 0.0007 | -0.8618 | 2.7442 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 7475.067 | 1.0431 | 1.0354 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.000427 | uM | 7475.067 | 0.9423 | 0.9512 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.00213 | uM | 7475.067 | 0.9696 | 0.9745 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0107 | uM | 7475.067 | 1.1958 | 1.1542 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.0533 | uM | 7475.067 | 0.5537 | 0.5646 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 0.267 | uM | 7475.067 | 0.4986 | 0.4980 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 1.33 | uM | 7475.067 | 0.4997 | 0.4994 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 6.67 | uM | 7475.067 | 0.2777 | 0.1747 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Ispinesib | KSP | Kinesin | 33.3 | uM | 7475.067 | 0.0011 | -0.8808 | 2.4078 |